A versatile CRISPR toolbox to study neurological CaV3.2 channelopathies by promoter-mediated transcription control
Despina Tsortouktzidis, Anna R. Tröscher, Herbert Schulz, Susanne Schoch, Albert J. Becker, Karen M. J. van Loo
The paper demonstrates a CRISPRa/i toolbox for manipulating the Cacna1h gene promoter to study CaV3.2 channelopathies in neuronal cells and tissues.
bioRxiv · Mar 20, 2021 · PreprintNeuroscience