Jae Young Choi

Biogeographic cline is associated with the global plant telomere length variation

The paper analyzes telomere length variation across 257 plant species and finds that biogeographic factors, not life-history traits, significantly influence telomere length.

Rapid evolution and functional divergence of the monkeyflower Mimulus lewisii telomerase

This study investigates rapid evolution of TERT in Mimulus lewisii and shows its functional divergence in binding TR paralogs, leading to telomere sequence changes and dominance in hybrids.

A near-complete human pancreatic cancer genome

This paper presents near-complete, haplotype-resolved assemblies of a pancreatic cancer genome and normal tissue, identifying extensive somatic variants and epigenetic changes in previously excluded regions.

Topsicle: a method for estimating telomere length from whole genome long-read sequencing data

Topsicle estimates telomere length from whole genome long-read sequencing data using k-mer and change point detection, showing robustness and accuracy in plant and human cancer cells.

Environment-dependent selection impacts heritable developmental stability and trait canalization in rice

This study investigates how environmental stress affects developmental stability and canalization in rice, finding that drought reduces canalization and identifies specific genes involved.

Evolutionary rate covariation analysis of E-cadherin identifies Raskol as regulator of cell adhesion and actin dynamics in Drosophila

The paper uses evolutionary rate covariation analysis to identify genes coevolving with Drosophila E-cadherin, revealing novel regulators of cell adhesion and actin dynamics.