Yang Hong

This paper uses AlphaFold for protein structure prediction and virtual screening to identify anti-schistosomal compounds, finding seven active compounds including Carubicin hydrochloride, which targets U2AF65 and disrupts parasite splicing.

This study identifies metabolic and ribosomal dysregulation as key factors causing developmental arrest of Schistosoma japonicum in non-permissive rats.

This study identifies an electrostatic mechanism by which Dlg localizes to the plasma membrane, contributing to cell polarity and tumorigenesis.

The paper uses evolutionary rate covariation analysis to identify genes coevolving with Drosophila E-cadherin, revealing novel regulators of cell adhesion and actin dynamics.