Line Bjørge

The paper uses single-cell RNA sequencing to identify resistance signatures in ovarian cancer and develops a framework for combination therapy with carboplatin.

This study develops a humanized xenograft model of high-grade serous ovarian cancer to evaluate immunotherapy, finding no treatment response but identifying immune-excluded tumor phenotypes.

This study identifies seven novel genetic loci associated with high-grade serous ovarian cancer risk using a large-scale GWAS and develops polygenic scores for improved risk prediction.

This study combines genome-wide association data from four cancers to identify shared and novel genetic associations and pleiotropic effects.