Author

Lynette Caitlin Mikula

Austrian Agency for Health and Food SafetyORCID 0000-0002-0252-4014Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Claus VogliD· 2 shared Adriana Cabal RoseliD· 1 shared Amy C. PickeringiD· 1 shared Buŗcin YıldırımiD· 1 shared Carolin KosioliD· 1 shared Helene MarbachiD· 1 shared Hrönn KjartansdóttiriD· 1 shared Igor LoncariciD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Claus VoglORCID

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2 papers

Recent·Most cited

A single transcriptional regulator is crucial for the adaptation of Staphylococcus aureus to diverse niches

Claus Vogl, Lynette Caitlin Mikula, Helene Marbach, Katharina Mayer-Weihrauch, Sebastian Herndler, Leonie Breitschopf, Amy C. Pickering, Mary-Elizabeth Jobson, Adriana Cabal Rosel, Nora Dinhopl, Igor Loncaric, Werner Ruppitsch, Lindsey Neil Shaw, Orla M. Keane, J. Ross Fitzgerald, , Tom Grunert

This study shows that the transcriptional regulator SigB is crucial for Staphylococcus aureus adaptation to different niches, with SigB-deficient strains evolving in persistent mastitis due to the cost of phenotypic plasticity.

bioRxiv · Aug 1, 2025 · PreprintMicrobiology

Inference of Genomic Landscapes using Ordered Hidden Markov Models with Emission Densities (oHMMed)

Claus Vogl, Mariia Karapetiants, Buŗcin Yıldırım, Hrönn Kjartansdóttir, Carolin Kosiol, Juraj Bergman, Michal Majka, Lynette Caitlin Mikula

The paper introduces oHMMed, a Hidden Markov Model for genomic segmentation, and applies it to analyze base composition, gene density, and chromatin features across multiple species.

BMC Bioinformatics · Apr 16, 2024Peer-reviewedBioinformatics