Author

Orla M. Keane

Teagasc - The Irish Agriculture and Food Development AuthorityORCID 0000-0002-9507-2191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adriana Cabal RoseliD· 1 shared Amy C. PickeringiD· 1 shared Claus VogliD· 1 shared Dagmara A. NiedzielaiD· 1 shared Finola Catherine LeonardiD· 1 shared Gilles FoucrasiD· 1 shared Helene MarbachiD· 1 shared Igor LoncariciD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMicrobiology

Adriana Cabal RoselORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A single transcriptional regulator is crucial for the adaptation of Staphylococcus aureus to diverse niches

Claus Vogl, Lynette Caitlin Mikula, Helene Marbach, Katharina Mayer-Weihrauch, Sebastian Herndler, Leonie Breitschopf, Amy C. Pickering, Mary-Elizabeth Jobson, Adriana Cabal Rosel, Nora Dinhopl, Igor Loncaric, Werner Ruppitsch, Lindsey Neil Shaw, Orla M. Keane, J. Ross Fitzgerald, , Tom Grunert

This study shows that the transcriptional regulator SigB is crucial for Staphylococcus aureus adaptation to different niches, with SigB-deficient strains evolving in persistent mastitis due to the cost of phenotypic plasticity.

bioRxiv · Aug 1, 2025 · PreprintMicrobiology

Bovine milk somatic cell transcriptomic response to Staphylococcus aureus is dependent on strain genotype

Dagmara A. Niedziela, Paul Cormican, Gilles Foucras, Finola Catherine Leonard, Orla M. Keane

This study examines how bovine milk somatic cells respond transcriptomically to two Staphylococcus aureus strains, finding strain-specific gene expression and immune pathway activation patterns.

bioRxiv · Mar 4, 2021 · PreprintGenomics