Author

Amy S Orr

Dartmouth CollegeORCID 0000-0002-0266-0390Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:yeast· 1

Frequent Co-Authors

Karina Lopes· 2 shared William T. WickneriD· 2 shared Jerry O'Dwyer· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBiochemistry

Karina Lopes

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2 papers

Recent·Most cited

BiochemistryMolecular Biology of the CellPeer-reviewedNov 19, 2025

Functional assembly of the Qc-SNARE with Sec18 and Sec17 on membranes

Amy S Orr, Karina Lopes, Jerry O'Dwyer, William T. Wickner

The paper investigates the functional assembly of Qc-SNARE with Sec18 and Sec17 on membranes, revealing their roles in yeast vacuolar fusion and ATP hydrolysis.

DOI 10.1091/mbc.e25-10-0474

yeastexperimental assay

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BiochemistrybioRxivPreprintNov 15, 2024

Membrane fusion reactions limited by defective SNARE zippering or stiff lipid fatty acyl composition have distinct requirements for Sec17, Sec18, and adenine nucleotide

Karina Lopes, Amy S Orr, William T. Wickner

This study investigates how defective SNARE zippering or stiff lipid fatty acyl composition affect membrane fusion and the roles of Sec17 and Sec18 in overcoming these impediments.

DOI 10.1101/2024.11.15.623832

experimental assaycell signaling & trafficking

𝕏 PostBluesky