Segmented regression to streamline semi-mechanistic pharmacodynamic modelling of antibiotic effects
Anh Duc Pham, Wisse van Os, Jorn Brink…·Linda B.S. Aulin
This paper introduces a three-step workflow using segmented regression to improve semi-mechanistic pharmacodynamic modeling of antibiotic effects, demonstrating it with colistin against Pseudomonas aeruginosa.