Daniel E. Rozen

A family of lanthipeptides with anti-phage function

The paper identifies a family of over 2000 lanthipeptide biosynthetic gene clusters in Actinobacteria with anti-phage function, demonstrating their conservation and novel compound production.

The influence of heteroresistance, growth and antibiotic selection in shaping the invasion dynamics of colistin resistant Pseudomonas aeruginosa

This study examines how heteroresistance, growth rates, and antibiotic selection affect the invasion dynamics of colistin-resistant Pseudomonas aeruginosa in co-culture with susceptible isolates.

Antibiotic production reduces the cost of resource cheaters in Streptomyces coelicolor

This study shows antibiotic production by Streptomyces coelicolor reduces the fitness advantage of resource-cheating bacteria on complex media but not on simple media.

Divergent spontaneous antibiotic-resistance evolution confers reciprocal and exploitable collateral sensitivity effects

This study identifies consistent collateral sensitivity interactions between antibiotics in S. pneumoniae and develops a model to guide treatment strategies.

Using BONCAT To Dissect The Proteome Of S. aureus Persisters

This study uses BONCAT to identify the proteome of S. aureus persisters under antibiotic stress, revealing upregulated pathways and downregulated processes involved in survival.

Bacterial heterozygosity promotes survival under multidrug selection

This study shows that bacterial heterozygosity increases survival under multidrug selection by allowing flexible chromosome ratio adjustments, reducing fitness costs compared to homozygous cells.

Being bigger is better: Size-dependent advantages of plasmodial fusion in a multinucleated slime mould

This study investigates plasmodial fusion in Physarum polycephalum, showing size-dependent survival benefits and increased fusion rates under abiotic stress, regardless of genetic relatedness.