MicrobiologybioRxivPreprint
The polysaccharide portion of LPS is critical for caspase-11 inflammasome activation
Matthew E. Sherman, Colton Sheehan, Luca Musante…·Sunny Shin
This study shows that the polysaccharide portion of LPS, not just lipid A acylation, is critical for Casp11 inflammasome activation and pyroptosis.
DOI 10.64898/2026.10.01.756121