Modesta Blunskyte-Hendley

This study shows parental care in burying beetles acts as a genetic capacitor, storing and releasing genetic variation in offspring body size through molecular mechanisms involving chaperones and chromatin state.

This study uses mouse models with tau mutations to show two distinct pathogenic mechanisms in tauopathies, with different progression patterns and responses to amyloid.

The paper identifies gene expression changes in microglia around Aβ plaques in human Alzheimer's disease tissue and finds cross-species concordance with mouse data.

This study uses bulk and single nuclear RNA-sequencing to analyze transcriptomic changes in repeat expansion ataxias, revealing distinct non-neuronal cell type-specific disease signatures across the human brain.