Sifan Yin

Biophysical basis for brain folding and misfolding patterns in ferrets and humans

The paper uses physical gel models and simulations to study brain folding in ferrets and links findings to human cortical malformations caused by genetic defects.

Morphogenesis and morphometry of brain folding patterns across species

This study uses physical experiments, computational models, and morphometric analysis to show that differential growth explains cortical folding across species.

Hox genes modulate physical forces to differentially shape small and large intestinal epithelia

This study shows Hoxd13 regulates hindgut morphogenesis through the TGFβ pathway by altering mesenchymal biomechanics.

Ethology of morphogenesis reveals the design principles of cnidarian size and shape development

The paper shows how muscular hydraulic behavior in Nematostella vectensis drives larva-polyp morphogenesis through antagonistic muscle pressures.