Clifford James Tabin

Human foregut morphogenesis exhibits murine-like molecular patterning but avian-like epithelial architecture

The paper compares human, mouse, and chick foreguts to show human foregut combines mouse-like molecular patterning with chick-like epithelial architecture, suggesting chick embryos are useful for studying human foregut malformations.

Shifts in embryonic oxygen levels cue heterochrony in limb initiation

The paper identifies differential oxygen levels as a driver of heterochrony in limb development between avian and mammalian embryos.

Late embryonic expansion of a novel bone ridge underlies the evolutionary transformation of cylindrically shaped forelimb bones into the flattened skeleton of the penguin flipper

The paper identifies late embryonic developmental changes in penguin forelimbs that lead to flattened bone morphology and reduced musculature, driven by molecular programs associated with tendon-attachment sites.

Early Pitx2 modulation of Fgf10 directs asymmetric lung morphology

This study identifies Fgf10 as a Pitx2-sensitive signal that drives asymmetric lung growth by modulating epithelial proliferation during early lung development.

Convergent flow-mediated mesenchymal force drives embryonic foregut constriction and splitting

This study identifies a biomechanical mechanism involving mesenchymal forces and SHH signaling that drives epithelial tube splitting during tracheal-esophageal separation in embryos.

Courtship vocalizations in male ducks: spectral composition and resonance of the syringeal bulla

This study investigates the role of the male duck syringeal bulla in courtship vocalizations by analyzing resonance frequencies and comparing them to vocalization spectra.

Integration of sexual dimorphism and left-right asymmetry in the development of the duck syrinx

The paper investigates how sexual dimorphism and left-right asymmetry interact in duck syrinx development, showing that PITX2 and estrogen signaling regulate asymmetric growth differently in males and females.

Hox genes modulate physical forces to differentially shape small and large intestinal epithelia

This study shows Hoxd13 regulates hindgut morphogenesis through the TGFβ pathway by altering mesenchymal biomechanics.

Direct Reprogramming of Non-limb Fibroblasts toCells with Properties of Limb Progenitors

This study reprograms non-limb fibroblasts into cells with limb progenitor properties using Prdm16, Zbtb16, Lin28, and Lin41.

A dynamic Hedgehog gradient orients tracheal cartilage rings

The paper investigates how a dynamic Hedgehog gradient organizes tracheal cartilage rings into parallel stripes through a Turing-like mechanism.

In ovo electroporation of chick limb bud ectoderm

This paper describes an in ovo electroporation method for manipulating gene expression in chick limb bud ectoderm, revealing Rac1's role in wound healing actin remodeling.

A chromosome level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution.

The paper presents a chromosome-level genome of surface fish Astyanax mexicanus and uses it to identify genetic factors contributing to trait evolution in cavefish populations.