Matthieu Sanial

This paper demonstrates a method to directly detect and quantify fluorescent proteins in gels, offering a faster, cheaper, and more sensitive alternative to immunoblotting.

The paper shows that CBP/EP300 acetylates and stabilizes HSF2, which is disrupted in Rubinstein-Taybi syndrome, leading to impaired heat shock response.

The paper shows that high Hedgehog signaling controls Smoothened's apico-basal distribution through a multikinase-dependent switch involving Protein Kinase A, Casein Kinase I, and Fused kinase.