Kristopher W. Brannan

This paper develops a long-lived human vascular avatar to model age-related vascular disease and aging using iPSC-derived cells.

This study shows that telomerase mRNA reduces radiation-induced DNA damage in human skin cells by enhancing DNA repair and reducing mitochondrial ROS without extending telomere length.

The paper constructs an RNA-aware RBP-centric PPI map across the mRNA life-cycle, revealing 20,359 novel interactions and showing 73% are RNA-dependent.

HydRA predicts RNA-binding capacity using protein interaction and sequence data, identifying novel RNA-binding domains with high specificity and sensitivity.