Fibroblast-derived thrombospondin-1 shapes macrophage polarization in advanced human co-culture models
Kristina Draganić, Sergey Isaev, Isabella Pototschnig…·Gerda Egger
This study uses advanced human co-culture models to show that fibroblast-derived thrombospondin-1 drives macrophage metabolic remodeling and polarization in tumor environments.