Angela Stout

Loss of SEZ6L2 disrupts synaptic architecture and drives progressive behavioral deficits

This study characterizes Sez6l2 knockout mice, showing behavioral and synaptic deficits, and compares them to Sez6 triple knockout mice, highlighting SEZ6L2's non-redundant role in brain function.

Sez6L2 autoimmunity induces cerebellar ataxia in mice

This study shows that Sez6L2 autoimmunity in mice causes cerebellar ataxia, with antibodies and T cells targeting Sez6L2 leading to mobility impairments and brain inflammation.

Hybrid Amyloid Quantum Dot Nanoassemblies to Probe Neuroinflammatory Damage

The paper develops a quantum dot mimetic to study the role of amyloid-beta oligomers in neuroinflammatory responses in neuronal and glial cells.

A Quantum Dot Biomimetic for SARS-CoV-2 to Interrogate Dysregulation of the Neurovascular Unit Relevant to Brain Inflammation

This study uses a SARS-CoV-2 biomimetic to investigate how BBB dysregulation may lead to neuroinflammation without direct viral infection.