Julia M. Granato

This study characterizes Sez6l2 knockout mice, showing behavioral and synaptic deficits, and compares them to Sez6 triple knockout mice, highlighting SEZ6L2's non-redundant role in brain function.

This study shows that genetic background affects SEZ6L2 autoimmunity, with SJL mice showing stronger immune responses and neurological dysfunction compared to C57BL/6 mice.

This study shows that Sez6L2 autoimmunity in mice causes cerebellar ataxia, with antibodies and T cells targeting Sez6L2 leading to mobility impairments and brain inflammation.