Base pair editing of goat embryos: nonsense codon introgression into FGF5 to improve cashmere yield
Guanwei Li, Shiwei Zhou, Chao Li, Bei Cai, Honghao Yu, Baohua Ma, Yu Shu Huang, Yige Ding, Yao Liu, Qiang Ding, Chong Z. He, Jiankui Zhou, Ying Wang, Guangxian Zhou, Yan Li, , Xiaolong Wang
This study uses base editing in goat embryos to introduce nonsense mutations in FGF5, improving cashmere yield with minimal off-target effects.
bioRxiv · Jun 15, 2018 · PreprintGenetics