Cell BiologybioRxivPreprint
Functional integrity of the SEL1L-HRD1 complex is critical for ERAD and organismal viability
Xiawei Zhang, Liangguang Leo Lin, Linxiu Pan…·Ling Qi
This paper shows that the SEL1L-HRD1 complex is essential for ERAD function and neonatal survival in mice, with specific mutations causing lethal defects.
DOI 10.1101/2025.08.01.668162