Author
University of VirginiaORCID 0000-0001-5764-3419Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Emir Maldosevic, Radoslaw J. Gora, Liangguang Leo Lin…·Ahmad Jomaa
This study identifies a molecular switch in NAC that prevents mitochondrial protein mistargeting by SRP, showing that mutations disrupt this mechanism and cause ER stress.
Xiawei Zhang, Liangguang Leo Lin, Linxiu Pan…·Ling Qi
This paper shows that the SEL1L-HRD1 complex is essential for ERAD function and neonatal survival in mice, with specific mutations causing lethal defects.
Huilun Helen Wang, Zhihong Wang, Liangguang Leo Lin…·Ling Qi
This study reports the discovery of using antisense oligonucleotides (ASOs) to rescue the biallelic SEL1L C141Y variant, offering a potential therapeutic strategy.