Author

Qiuzhen Chen

Shandong UniversityORCID 0000-0002-0344-2096Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:protein structure prediction· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Junhao WangiD· 2 shared Tong ZhouiD· 2 shared Chang LiuiD· 1 shared Chikun WangiD· 1 shared Hanwen ZhangiD· 1 shared Huanyu YaniD· 1 shared Jiale HeiD· 1 shared Jilin ZhangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioinformatics

Junhao WangORCID

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Author profile →

3 papers

Recent·Most cited

Augmented prediction of multi-species protein--RNA interactions using evolutionary conservation of RNA-binding proteins

Jiale He, Tong Zhou, Lu‐Feng Hu, Yuhua Jiao, Junhao Wang, Shengwen Yan, Siyao Jia, Qiuzhen Chen, Wentao Zhu, Jilin Zhang, Mutian Jia, Yuanning Li, Xianwei Wang, Yangming Wang, Yucheng T. Yang, Lei Sun

MuSIC predicts cross-species RBP-RNA interactions using evolutionary conservation and label smoothing, outperforming existing methods and quantifying variant effects on binding.

Nature Communications · Apr 27, 2026Peer-reviewedBioinformatics

Plat safeguards maternally aged oocytes against programmed cell death through activating the Erk1/2 pathway

Xianying He, Hanwen Zhang, Ya Wang, Huanyu Yan, Qiuzhen Chen, Min Su, Qiaozhen Shi, Xiao Zeng, Wei Sheng, Yangmin Wang, Chikun Wang, Shuyue Hou, Zhibin Hu, Yuanlin He, Xi Wang

This study identifies Plat's role in protecting aged oocytes from programmed cell death by activating the Erk1/2 pathway, showing tPA supplementation improves oocyte quality.

Science China Life Sciences · Nov 13, 2025Peer-reviewedDevelopmental Biology

Integrating Mutation and Stop Signals for Improved RNA Structure Analysis and Insight Discovery

Tong Zhou, Ruobin Zhao, Shaozhen Yin, Yifan Hong, Junhao Wang, Xitong Liu, Qiuzhen Chen, Yuancheng Wang, Chang Liu, Lei Sun

STONE improves RNA structure analysis by integrating mutation and stop signals from a single experiment, enhancing coverage and accuracy in single-cell data.

bioRxiv · Oct 8, 2025 · PreprintBioinformatics