Molecular BiologyCommunications BiologyPeer-reviewed
Determinants of species-specific utilization of ACE2 by human and animal coronaviruses
Qingxing Wang, Sabrina Noettger, Qinya Xie…·Frank Kirchhoff
The paper identifies key mutations in SARS-CoV-2 and bat coronaviruses that affect ACE2 receptor usage across different species and shows that vaccinated individuals' sera neutralize bat Sarbecovirus Spike proteins.