Genetic & Genomic MedicinemedRxivPreprint
Integrative transcriptomic analysis identifies long noncoding RNA dysregulation and circadian disruption in reward and executive circuits of opioid use disorder
DOI 10.64898/2026.02.14.26346327
Author
Chan Zhou
University of Massachusetts Chan Medical SchoolORCID 0000-0002-0351-6235Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2017-2026 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship6 papers
Recent·Most cited
- Genetic & Genomic MedicinemedRxivPreprint
Frequent lncRNA-derived fusions in pediatric neuroblastoma identified by LncFusion: potential biomarker and therapeutic implications
Zixiu Li, Joae Wu, Peng Zhou, Chan Zhou
The paper identifies over 900 lncRNA-derived fusions in pediatric neuroblastoma using LncFusion, revealing their potential as biomarkers and therapeutic targets.
1 citation - BioinformaticsbioRxivPreprint
BAMBI: Integrative biostatistical and artificial-intelligence method discover coding and non-coding RNA genes as biomarkers
Peng Zhou, Zixiu Li, Feifan Liu…·Chan Zhou
BAMBI identifies coding and non-coding RNA genes as biomarkers for disease diagnosis and prognosis with high accuracy and biological interpretability.
1 citation - BioinformaticsbioRxivPreprint
Flnc: Machine Learning Improves the Identification of Novel Full-length Long Noncoding RNAs from RNA Sequencing Data Without Transcriptional Initiation Profiles
Zixiu Li, Peng Zhou, Euijin Kwon…·Chan Zhou
Flnc improves lncRNA identification from RNA-seq data by using machine learning, achieving over 85% accuracy without requiring H3K4me3 profiles.
1 citation - Molecular BiologyNature Cell BiologyPeer-reviewed
lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation
Kaveh Daneshvar, M. Behfar Ardehali, Isaac A. Klein…·Alan C. Mullen
This study shows that lncRNA DIGIT and BRD3 form phase-separated condensates to regulate endoderm differentiation by interacting with H3K18ac regions.
164 citationstop 1% - BioinformaticsbioRxivPreprint
Identification and characterization of m6A circular RNA epitranscriptomes
Chan Zhou, Benoit Molinié, Kaveh Daneshvar…·Alan C. Mullen
The paper identifies and characterizes m6A methylated circular RNAs, showing cell-type specificity and cross-talk with m6A-mRNAs through YTHDF2.
4 citations