Author

Kenichi Makino

Immunology Frontier Research Center, The University of OsakaORCID 0000-0002-0359-3038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:CITE-seq· 1 Approach:contrastive learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Kelvin Y. CheniD· 2 shared Kenji IchiyamaiD· 2 shared Mayu Hata· 2 shared Shimon SakaguchiiD· 2 shared Tatsuya Kibayashi· 2 shared Yusuke TakeshimaiD· 2 shared André Luiz Zorzetto-FernandesiD· 1 shared Anne BitoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersGenomics

Kelvin Y. ChenORCID

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2 papers

Recent·Most cited

Massively multiplex multimodal chemical screens at single-cell resolution

Kelvin Y. Chen, Romain Lopez, Basak Eraslan, Mayu Hata, Yusuke Takeshima, Kenichi Makino, Tatsuya Kibayashi, Kenji Ichiyama, Anne Biton, Jan-Christian Huetter, Anshul Bharat Kundaje, Jonathan K. Pritchard, Aviv Regev, Shimon Sakaguchi

The paper introduces a framework for multimodal chemical screens combining RNA, protein, and epigenomic readouts, revealing compound-specific mechanisms and off-target effects in T cells.

bioRxiv · May 27, 2026 · PreprintGenomics

Joint single-cell measurements of surface proteins, intracellular proteins and gene expression with icCITE-seq

Kelvin Y. Chen, Yusuke Takeshima, André Luiz Zorzetto-Fernandes, Kenichi Makino, Tatsuya Kibayashi, Mayu Hata, Kenji Ichiyama, Joshua D. Croteau, Kevin Taylor, Shimon Sakaguchi

This paper introduces icCITE-seq, a method that simultaneously measures surface and intracellular proteins and gene expression in single cells, validated in primary human T cells.

bioRxiv · Jan 11, 2025 · PreprintImmunology