Yuan-De Tan

This study shows miR-29a reprograms exhausted CD8 T cells into a stem-like state, enhancing their effector function and response to checkpoint inhibitors.

The paper identifies a tumor-suppressor gene signature that improves prognosis and relapse prediction in adenocarcinoma non-small cell lung cancer across multiple cohorts.

This paper shows that KSHV uses eIF5B to mimic hypoxia and support viral replication and oncogenesis by altering translation initiation.