Author

Christine Isabelle Rafie

University of MiamiORCID 0000-0002-2917-7016Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

Erietta StelekatiiD· 2 shared Natasha Karishma Khatwani· 2 shared Abigail HaffeyiD· 1 shared Alejandro V. VillarinoiD· 1 shared Anna BianchiiD· 1 shared Aristeidis G. TelonisiD· 1 shared Ashish Shah· 1 shared Asmita PathakiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

Erietta StelekatiORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 28, 2026

MicroRNA-29a enhances and preserves stem-like CD8 T cell differentiation by regulating master epigenetic circuits of exhaustion.

Xuebing Leng, Lance Alec Buchness, Christine Isabelle Rafie…·Erietta Stelekati

This study shows miR-29a reprograms exhausted CD8 T cells into a stem-like state, enhancing their effector function and response to checkpoint inhibitors.

DOI 10.64898/2026.05.25.727439

humanbulk RNA-seq

ImmunologybioRxivPreprintApr 3, 2026

Pharmacologic DPP-4 inhibition promotes CD8⁺ T cell metabolic fitness to enhance anti-tumor activity

Oriana Teran Pumar, Elton L VanNoy, Abigail Haffey…·Defne Bayık

This study shows that DPP-4 inhibition improves CD8+ T cell metabolism and anti-tumor activity in preclinical and clinical settings.

DOI 10.64898/2026.03.31.715681

mousehuman

Cancer BiologyCancer Immunology ImmunotherapyPeer-reviewedJun 23, 2025

Cell-specific nanoengineering strategy disrupts tolerogenic signaling from myeloid-derived suppressor cells to invigorate antitumor immunity in pancreatic cancer

Nilesh Deshpande, Anna Bianchi, Haleh Amirian…·Jashodeep Datta

The paper develops CXCR2-homing nanoparticles to specifically target PMN-MDSCs in PDAC, reducing arginase activity and enhancing T-cell activity without causing neutropenia.

10 citations

mouseexperimental assay