Author

Lance Alec Buchness

University of Miami

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alejandro V. VillarinoiD· 1 shared Aristeidis G. TelonisiD· 1 shared Benjamin CurralliD· 1 shared Christine Isabelle RafieiD· 1 shared Corneliu M. Sologon· 1 shared Erietta StelekatiiD· 1 shared Jashodeep DattaiD· 1 shared Kevin Van der JeughtiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alejandro V. VillarinoORCID

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1 paper

Recent·Most cited

MicroRNA-29a enhances and preserves stem-like CD8 T cell differentiation by regulating master epigenetic circuits of exhaustion.

Xuebing Leng, Lance Alec Buchness, Christine Isabelle Rafie, Panagiotis Vlantis, Svetlana Ristin, Margaret Gallardo, Supipi Liyamali Auwardt, Natasha Karishma Khatwani, Yuan-De Tan, Yuguang J. Ban, Corneliu M. Sologon, Benjamin Currall, Siôn Llewelyn Williams, Kevin Van der Jeught, Jashodeep Datta, , Erietta Stelekati

This study shows miR-29a reprograms exhausted CD8 T cells into a stem-like state, enhancing their effector function and response to checkpoint inhibitors.

bioRxiv · May 28, 2026 · PreprintImmunology