Author

Lisa Amrhein

Helmholtz MunichORCID 0000-0002-0370-624XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Christiane FuchsiD· 2 shared Björn Eismann· 1 shared Christian ConradiD· 1 shared Claudia R. BalliD· 1 shared Fabian Joachim TheisiD· 1 shared Friedrich PreußeriD· 1 shared Hanno GlimmiD· 1 shared Ivo Glynne GutiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Christiane FuchsORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 5, 2019

A mechanistic model for the negative binomial distribution of single-cell mRNA counts

Lisa Amrhein, Kumar Harsha, Christiane Fuchs

The paper investigates the mechanistic model underlying the negative binomial distribution of single-cell mRNA counts, showing it arises from bursty transcription.

31 citations

scRNA-seqstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintSep 12, 2018

pheno-seq - linking morphological features to gene expression in 3D cell culture systems

Stephan M. Tirier, Jeongbin Park, Friedrich Preußer…·Christian Conrad

The paper introduces pheno-seq, a method that links morphological features to gene expression in 3D cell cultures, showing its ability to identify morphology-specific genes and regulatory states not captured by scRNA-seq.

DOI 10.1101/311472

humanscRNA-seq

𝕏 PostBluesky