GenomicsNucleic Acids ResearchPeer-reviewed
Genomic transcription factor binding site selection is edited by the chromatin remodeling factor CHD4
Mika Saotome, Deepak Balakrishnan Poduval, Sara A. Grimm…·Motoki Takaku
This study shows CHD4 prevents inappropriate gene activation by editing transcription factor binding site selection through chromatin remodeling in breast cancer cells and during reprogramming.