Author

Brock J. Grill

University of WashingtonORCID 0000-0002-0379-3267Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:fluorescence / live-cell microscopy· 1 Research Focus:gene regulatory network inference· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Joseph S. PakiD· 2 shared Karla J. OppermaniD· 2 shared Muriel DesboisiD· 2 shared Anza DarehshouriiD· 1 shared Benjamin ScholliD· 1 shared Charu KapiliD· 1 shared Connon Thomas· 1 shared Damon T. PageiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Joseph S. PakORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 25, 2025

In vivo imaging of autophagy dynamics in the intact mammalian brain using a fluorescence lifetime-based sensor

Maya Maman, Kota Ando, Natalie Fisher…·Tal Laviv

The paper develops a fluorescence lifetime-based sensor to image autophagy dynamics in vivo, revealing spatial and activity-dependent patterns in the mouse brain.

DOI 10.64898/2025.12.25.693346

mousefluorescence / live-cell microscopy

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 28, 2025

UBR-1 enzyme network regulates glutamate homeostasis to affect organismal behavior and developmental viability

Joseph S. Pak, Seamus R. Morrone, Karla J. Opperman…·Brock J. Grill

This study identifies UBR-1 as a hub regulating glutamate homeostasis through a signaling axis, affecting locomotion and developmental viability in C. elegans.

DOI 10.1101/2025.07.28.666006

C. elegansproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 15, 2023

Axon development is regulated at genetic and proteomic interfaces between the integrin adhesome and the RPM-1 ubiquitin ligase signaling hub

Jonathan Amezquita, Muriel Desbois, Karla J. Opperman…·Brock J. Grill

The paper identifies genetic and proteomic interactions between the integrin adhesome and the RPM-1 ubiquitin ligase signaling hub in C. elegans neurons, showing their role in axon development and neurodevelopmental disorders.

DOI 10.1101/2023.11.15.566604

C. elegansproteomics

𝕏 PostBluesky