The paper examines diagnostic transitions and remission in eating disorders using polygenic scores in a Danish cohort, finding significant genetic associations with these outcomes.

Biological Psychiatry · Jan 17, 2025Peer-reviewedGenetic & Genomic Medicine

Paternal-age-related de novo mutations and risk for five disorders

Jacob L. Taylor, Jean-Christophe Debost, Sarah U. Morton, Emilie M. Wigdor, Henrike Heyne, Dennis Lal, Daniel P. Howrigan, Alex Bloemendal, Janne Tidselbak Larsen, Jack A. Kosmicki, Daniel J. Weiner, Jason G. Homsy, Jonathan G. Seidman, Christine E. Seidman, Esben Agerbo, , Elise Robinson

The paper estimates the risk of five disorders from paternal-age-related de novo mutations using whole-exome-sequencing data and Danish registry data.

Nature Communications · Jul 10, 2019Peer-reviewedGenetics

The Anorexia Nervosa Genetics Initiative: Overview and Methods

Laura Marie Thornton, Melissa A. Munn‐Chernoff, Jessica H. Baker, Anders Juréus, Richard Parker, Anjali K. Henders, Janne Tidselbak Larsen, Liselotte Vogdrup Petersen, Hunna J. Watson, Zeynep Yılmaz, Katherine M. Kirk, Scott D. Gordon, Virpi Leppä, Felicity C. Martin, David C. Whiteman, , Cynthia Marie Bulik

The paper describes the methods and recruitment strategies of the Anorexia Nervosa Genetics Initiative (ANGI), which successfully enrolled 13,364 individuals with AN and controls for genetic research.

Contemporary Clinical Trials · Oct 1, 2018Peer-reviewedGenetics