Anjali K. Henders

The paper investigates polygenic and familial factors influencing antidepressant treatment outcomes in two cohorts, finding associations between depression polygenic scores and treatment switching, with some links to schizophrenia and bipolar disorder.

The paper describes the AMBER program's cohort profile, collecting questionnaire data on antidepressant response from Generation Scotland participants to develop phenotypes and link with biological data.

The paper identifies polygenic score differences between antidepressant responders and difficult-to-treat depression groups in the AGDS:Cell-o cohort, suggesting biological distinctions and potential for early stratification.

This study explores South Asian Australians' health beliefs about cardiovascular disease and genomic testing, finding positive attitudes toward genomic testing but concerns about effectiveness and access.

This study identifies trace-level cytokines in PASC patients linked to cardiovascular symptoms and shows their impact on cardiomyocyte function using nanotechnology detection.

The paper introduces a method to compress genetic data using autoencoders that leverage linkage disequilibrium structure, achieving high reconstruction accuracy while reducing data size.

The paper identifies tissue-informative DNA methylation sites in ALS using targeted sequencing and machine learning, showing accurate prediction of disease status and progression.

The paper performs RNA-seq analysis of skeletal muscle in ALS patients and controls to identify differentially expressed genes and isoform switches associated with motor neuron disease.

This study conducts a genome-wide association meta-analysis of childhood aggression across multiple raters, instruments, and ages, identifying genetic correlations with various traits but no genome-wide significant SNPs.

This study identifies cell types associated with brain complex traits using GWAS and single-cell transcriptomics, revealing novel roles for oligodendrocytes in Parkinson's disease.

The paper replicates 55,000 DNA methylation QTLs using two cohorts and finds enrichment of trans mQTLs in specific genomic regions and complex traits.

This paper identifies novel pleiotropic risk loci for melanoma and nevus density, implicating multiple biological pathways and gene expression under MITF regulation.

The paper improves age prediction from DNA methylation using larger datasets, showing reduced error and limitations in capturing biological ageing variation.

The paper describes the methods and recruitment strategies of the Anorexia Nervosa Genetics Initiative (ANGI), which successfully enrolled 13,364 individuals with AN and controls for genetic research.