Kar‐Tong Tan

This study presents complete subtelomeric sequences from diverse populations, revealing extensive haplotype diversity and gene copy-number variation associated with chromosome arms.

This paper resolves ring chromosomes, Robertsonian translocations, and complex structural variants using long-read sequencing and telomere-to-telomere assembly, revealing breakpoint structures and methylation changes.

The paper uses long-read sequencing to identify four types of telomere repeat variations in cancer genomes, including neotelomeres and telomere-spanning fusions.

The paper develops a nanopore sequencing method to measure telomere length and finds chromosome-specific and conserved telomere lengths across individuals.

The paper identifies repeat-calling errors in nanopore sequencing of telomeres and shows that tuning basecalling models improves telomere analysis.