Author

Mitchell L. Leibowitz

Broad InstituteORCID 0000-0003-1874-5441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

Cheng‐Zhong ZhangiD· 1 shared David S. PellmaniD· 1 shared Heng LiiD· 1 shared Jidong ShaniD· 1 shared Kar‐Tong TaniD· 1 shared Lili Sun· 1 shared Logan J. BlaineiD· 1 shared Matthew M. MeyersoniD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Cheng‐Zhong ZhangORCID

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2 papers

Recent·Most cited

GenomicsCell GenomicsPeer-reviewedJun 24, 2024

Neotelomeres and Telomere-Spanning Chromosomal Arm Fusions in Cancer Genomes Revealed by Long-Read Sequencing

Kar‐Tong Tan, Michael K. Slevin, Mitchell L. Leibowitz…·Matthew M. Meyerson

The paper uses long-read sequencing to identify four types of telomere repeat variations in cancer genomes, including neotelomeres and telomere-spanning fusions.

17 citationstop 4%

humanwhole-genome sequencing

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GeneticsNature GeneticsPeer-reviewedApr 12, 2021

Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing

Mitchell L. Leibowitz, Stamatis Papathanasiou, Phillip A. Doerfler…·David S. Pellman

This paper shows that CRISPR-Cas9-induced DNA breaks can lead to chromothripsis, a catastrophic chromosomal rearrangement, which is an on-target toxicity in genome editing.

585 citationstop 1%

humanwhole-genome sequencing

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