Jacques Prost

The paper studies how vortex topological defects in myoblast monolayers drive the formation of 3D cell mounds through converging cell flows.

This study identifies fibrillar adhesions as the primary integrin complexes that respond to matrix topography, forming independently of focal adhesions.

This study demonstrates that epithelial tissue homeostasis is maintained through active trans-epithelial fluid flow, not cell contractility, using an in vitro model of micro-sized hydrogel spheres.