MicrobiologybioRxivPreprint
Escape from antimicrobial CRISPR-Cas9 in E. coli ST131 depends on the genetic context of the target gene.
Clàudia Morros-Bernaus, Joseph Westley, Ethan R. Wyrsch…·Stineke van Houte
This study investigates CRISPR-Cas9 antimicrobial activity against E. coli ST131 and identifies two escape mechanisms, showing that genetic context of the target gene influences escape frequency.
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