David Sünderhauf

This study demonstrates that mobile CRISPR-Cas9 tools can effectively prevent the dissemination of an AMR plasmid from K. pneumoniae to E. coli under various experimental conditions.

This study shows that plasmid-borne CRISPR-Cas is beneficial in plasmid competition but is hindered by toxin-antitoxin systems in horizontally transferred plasmids.

This study investigates CRISPR-Cas9 antimicrobial activity against E. coli ST131 and identifies two escape mechanisms, showing that genetic context of the target gene influences escape frequency.