William H. Gaze

This study reviews and analyzes longitudinal data on antibiotic resistance in beef cattle, finding increased resistance during and after antibiotic use, with time-dependent effects.

This paper refines the SELECT method to predict no effect concentrations for resistance (PNECRs) of 32 antibiotics, aiding environmental risk assessments by ranking antibiotics based on their potential to select for antimicrobial resistance.

This study shows that plasmid-borne CRISPR-Cas is beneficial in plasmid competition but is hindered by toxin-antitoxin systems in horizontally transferred plasmids.

This study investigates CRISPR-Cas9 antimicrobial activity against E. coli ST131 and identifies two escape mechanisms, showing that genetic context of the target gene influences escape frequency.

This study assesses the antimicrobial effects and AMR selection potential of non-antibiotic drugs on bacterial communities using metagenomic and metatranscriptomic analyses.

This study shows that non-antibiotic drugs enhance the selection of antimicrobial resistance when combined with ciprofloxacin, altering community composition and increasing resistance gene prevalence.