Mantang Qiu

This paper introduces an adjuvant (iCTA) that enhances in vivo CAR-T therapy against solid tumors by improving T-cell recruitment, antigen presentation, and tumor microenvironment.

This paper develops a lipid nanoparticle strategy to enhance CAR-T cell persistence and antitumour efficacy in solid tumours by targeting primary lymphoid tissues.

TIP-seq enables simultaneous transcriptome and protein profiling in single cells, revealing immune checkpoint interactions and tumor microenvironment dynamics in NSCLC.

This study identifies sympathetic signals promoting immunosuppressive neutrophils in lung tumors and shows that blocking these signals enhances immunotherapy.