Fuping You

This paper introduces an adjuvant (iCTA) that enhances in vivo CAR-T therapy against solid tumors by improving T-cell recruitment, antigen presentation, and tumor microenvironment.

This study shows that MNS reduces viral infection and inflammation in cell and animal models by suppressing inflammatory pathways and altering chromatin accessibility.

This paper shows Betrixaban activates cGAS and ERVs to trigger antiviral immunity through dual pathways, suggesting its repurposing as a broad-spectrum antiviral.

This study identifies IgG's pro-atherogenic role through noncanonical activation of macrophages, independent of its classical function, by acting as a TLR4 ligand and promoting inflammation.

This paper introduces DeepAVC, a framework using pre-trained large language models to predict broad-spectrum antiviral compounds, achieving high accuracy and identifying novel compounds with experimental validation.

CBRPP identifies RNA-associated proteins in native cells without cross-linking or RNA manipulation.