Author

O Knight

Humboldt-Universität zu BerlinORCID 0000-0002-0424-2379Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Chiara RomagnaniiD· 2 shared Timo RückertiD· 2 shared Adam P. CroftiD· 1 shared Anne Sae Lim von StuckradiD· 1 shared Chiara GiordanoiD· 1 shared Chrissy BoltoniD· 1 shared Christopher B. MahonyiD· 1 shared Cornelia Winning· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Chiara RomagnaniORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 18, 2026

✦ In-depth digest

Somatic genetic variation shapes clonal selection of memory NK cells

Timo Rückert, Matthias Günther, Oliver Knight…·Chiara Romagnani

Whole-exome sequencing of memory NK cells from 81 CMV-seropositive donors reveals dominant somatic clones, early-life origin, and positive selection, with Kmt2d loss shifting mouse NK fitness.

1 citation

humanmouse

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ImmunologybioRxivPreprintMay 29, 2026

Tissue-adapted NK cells shape pathogenic cDC1 niches in early arthritis

O Knight, Chiara Giordano, Anne Sae Lim von Stuckrad…·Chiara Romagnani

The paper identifies NK cells as key orchestrators of adaptive immune niches in early arthritis by upregulating XCL1, which recruits XCR1+ cDC1s, forming pathogenic modules that correlate with disease severity.

DOI 10.64898/2026.05.01.716870

humanbulk RNA-seq

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