Hae Ryong Kwon

This study identifies STAT5-IGF1 signaling as a pathway driven by constitutive PDGFRb activation that causes connective tissue overgrowth in mice, with implications for human disease.

This study identifies STAT1 as a suppressor of PDGFRβ-driven overgrowth in a mouse model of KOSAKI overgrowth syndrome.

This study shows that overactive PDGFRα and PDGFRβ signaling in mice leads to distinct but overlapping fibrotic and growth-related muscle changes, with sex-specific effects.

The paper investigates the role of Rac1 and SRF in cranial development, showing their necessity for maintaining mechanosensing mesenchyme in mice.

The paper traces adipocyte dedifferentiation into fibroblast-like cells at skin wounds using lineage tracing and identifies PDGF and TGFβ signaling as promoting this process.

This study shows that a PDGFRβ mutation causes skeletal stem cell defects leading to osteopenia and overgrowth in mice by altering osteogenic and chondrogenic pathways.