Cancer BiologybioRxivPreprint
Temporal multi-modal single-cell analyses reveal dynamic interactions of CAR-T cells with glioblastoma and targeting of antigen-negative neoplastic cells
Daniel Y. Zhang, Xin Wang, Yusha Y. Sun…·Hongjun Song
This study uses temporal multi-modal single-cell profiling to show CAR-T cells interact dynamically with glioblastoma cells, including antigen-negative ones, and reduce their proliferation through IFN-gamma.