Spatial control of myosin regulatory light chain phosphorylation modulates cardiac thick filament mechano-sensing
Caterina Squarci, Daniel Koch, Paul Anaya, Kenneth S. Campbell, Thomas Kampourakis
This study shows that phosphorylation of cardiac myosin regulatory light chain (RLC) is spatially controlled and modulates mechano-sensing in cardiac thick filaments.
Proceedings of the National Academy of Sciences · Feb 5, 2026Peer-reviewedBiochemistry