Thomas Kampourakis

This study shows that cMLCK forms biomolecular condensates that enhance myosin motor phosphorylation in cardiac muscle cells, revealing a mechanism for regulating heart contractile function.

This paper uses simulations to show that concentric and eccentric cardiac growth are regulated by ATP homeostasis and titin-based stress, respectively, and can model growth patterns from both genetic and clinical causes.

This study shows that phosphorylation of cardiac myosin regulatory light chain (RLC) is spatially controlled and modulates mechano-sensing in cardiac thick filaments.

The paper measures how mavacamten and deoxyATP affect the SRX/DRX ratio in porcine cardiac myofibrils using a fluorescence imaging approach.

GelBox improves rigor and reproducibility in gel and immunoblot analysis by integrating image adjustments, background correction, band-fitting, and metadata association in a single open-source tool.