Alexis L. Norris

The paper describes a method using in vitro transcribed guideRNAs for targeted nanopore sequencing to study structural variations in pancreatic cancer cell lines.

The paper analyzes whole genome sequencing data from genome-edited cattle and identifies unintended plasmid integration at the target site.

The paper introduces RIDAR, a method to reduce computational load in isobaric proteomics by filtering MS/MS spectra before database searching, achieving an 85% time reduction on a standard desktop.

This study demonstrates that nanopore sequencing can effectively detect structural variants in cancer, particularly large deletions, inversions, and translocations, with high sensitivity at low read counts.