Yunfan Fan

Three annotated chromosome-level de novo genome assemblies of Lomentospora prolificans provide evidence for a chromosomal translocation event

This study presents three chromosome-level genome assemblies of Lomentospora prolificans, revealing a chromosomal translocation event between strains.

Comprehensive screening of a light-inducible split Cre recombinase with domain insertion profiling

The paper develops a pooled library screening method with a Bayesian approach to improve prediction of split protein behavior using light-inducible Cre recombinase.

Human and murine Cryptococcus neoformans infection selects for common genomic changes in an environmental isolate.

The paper shows that environmental Cryptococcus neoformans strains undergo genomic and phenotypic changes during mammalian infection, suggesting animal virulence drives genetic adaptation.

Genome and transcriptome of a pathogenic yeast, Candida nivariensis

The paper presents a highly contiguous genome and transcriptome of Candida nivariensis, assembled using Oxford Nanopore and Illumina sequencing.

De novo genome assembly of the Tobacco Hornworm moth (Manduca sexta)

This paper presents a new, more continuous and accurate reference genome for the Tobacco Hornworm moth using modern assembly techniques.

Targeted nanopore sequencing by real-time mapping of raw electrical signal with UNCALLED

UNCALLED enables real-time targeted nanopore sequencing by mapping raw electrical signals to references, improving coverage and variant detection in bacterial and human genomes.

Nanopore sequencing detects structural variants in cancer

This study demonstrates that nanopore sequencing can effectively detect structural variants in cancer, particularly large deletions, inversions, and translocations, with high sensitivity at low read counts.