Author

Emily K.W. Lo

Johns Hopkins UniversityORCID 0000-0002-0449-8083Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Patrick CahaniD· 3 shared Adrian IdriziiD· 1 shared Andrew P. FeinbergiD· 1 shared Chulan KwoniD· 1 shared Da PengiD· 1 shared Hongkai JiiD· 1 shared Jeremy J. VelazqueziD· 1 shared Mo R. EbrahimkhaniiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

Patrick CahanORCID

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Author profile →

3 papers

Recent·Most cited

DNA methylation memory of pancreatic acinar-ductal metaplasia transition state altering Kras-downstream PI3K and Rho GTPase signaling in the absence of Kras mutation

Emily K.W. Lo, Adrian Idrizi, Rakel Tryggvadóttir, Weiqiang Zhou, Wenpin Hou, Hongkai Ji, Patrick Cahan, Andrew P. Feinberg

The paper investigates DNA methylation changes during pancreatic acinar-ductal metaplasia (ADM) and their persistence without Kras mutation, linking epigenetic memory to signaling pathway alterations and cancer cell plasticity.

Genome Medicine · Mar 28, 2025Peer-reviewedCancer Biology

Platform-Agnostic CellNet (PACNet) enables cross-study meta-analysis of cell fate engineering protocols

Emily K.W. Lo, Jeremy J. Velazquez, Da Peng, Chulan Kwon, Mo R. Ebrahimkhani, Patrick Cahan

PACNet enables platform-agnostic comparison of cell fate engineering protocols by analyzing transcriptomic data from multiple studies and identifying best practices and off-target effects.

bioRxiv · Sep 7, 2022 · PreprintDevelopmental Biology

Radiator: a cloud-based framework for deploying reusable bioinformatics tools

Emily K.W. Lo, Remy M Schwab, Zak Burke, Patrick Cahan

The paper introduces Radiator, a cloud-based framework for deploying bioinformatics tools as web applications, and describes its implementation and availability.

bioRxiv · Apr 20, 2019 · PreprintBioinformatics