Stewart Alan Factor

Human-genome gut-microbiome interaction in Parkinson's disease

The paper shows that genetic variants at the alpha-synuclein locus influence gut microbiome dysbiosis in Parkinson's disease.

A Metabolomic Study of Cervical Dystonia

This study conducts a metabolomics analysis of cervical dystonia, identifying 289 significant metabolic differences and 9 associated biological pathways.

Integrated Proteomics Reveals Brain-Based Cerebrospinal Fluid Biomarkers in Asymptomatic and Symptomatic Alzheimer’s Disease

The paper identifies brain-linked CSF biomarkers in Alzheimer’s disease using proteomics, revealing altered levels in both brain and CSF across different disease stages.

Characterizing dysbiosis of gut microbiome in PD: Evidence for overabundance of opportunistic pathogens

This study identifies three clusters of gut microbiota associated with Parkinson's disease, including overabundance of opportunistic pathogens.

Perception of whole-body motion during balance perturbations is impaired in Parkinson’s disease and is associated with balance impairment

This study finds that Parkinson’s disease patients have impaired perception of whole-body motion during balance perturbations, which correlates with worse balance ability.

Levodopa Responsiveness Subtypes of Freezing of Gait: Results Using a Levodopa Challenge

This study identifies distinct subtypes of freezing of gait in Parkinson's disease based on levodopa responsiveness, showing ONOFF-FOG differs from OFF-FOG in clinical outcomes and response to treatment.

Lower-limb rigidity is associated with frequent falls in Parkinson disease

The paper investigates the association between lower-limb rigidity and frequent falls in Parkinson's disease using logistic regression analysis of clinical data.